I don't think that much will change regarding to Replicate's API because of Cloudflare. It's specifically mentioned in Replicate's blog post and it's also not in their best interest.
What's important to know ( I think). Recently, Cloudflare released a blog post of Omni for AI inference. I think they performance tuned it better than other providers. So their costs per inference drops down a lot ( https://blog.cloudflare.com/how-cloudflare-runs-more-ai-mode... ). Since the performance is OK, they now want to expand usage and their model catalog.
Replicate is a perfect fit. Model catalog, infrastructure for larger models, more specialised tools for fine-tuning, ...
Eg. For inference, Replicate is basically just a Worker AI endpoint and easy to maintain. Fine-tuning could probably be something similar.
But then again, that's my 2 cents. It was already mentioned that Replicate will stay as a distinct brand.