Last year, I started setting up a Qubes OS workstation. Doing all the intricate little steps manually seemed like such a waste of time that I started learning SaltStack, which is built into the Qubes management stack, to be able to automate and replicate the setup. This small itch exploded in such a way that I wrote a formula for almost every program on every system and server I use. For all other small programs, I just use one formula that syncs the appropriate dotfiles (I can also template them with Jinja).

In hindsight, going with Nix would have been the most efficient way to reach most of that, apart from the Qubes-specific stuff. This will probably be the next step on my (ironic) odyssey of going all-in on configuration to finally stop worrying about it and reap the benefits of the beauty that is computing without its nasty warts.

In essence, I would love a proper integration between Nix and Qubes OS.

Edit: For anyone interested in an example of my current process, see https://github.com/lkubb/salt-tool-chromium-formula, https://github.com/lkubb/salt-tool-gpg-formula or https://github.com/lkubb/salt-tool-macos-formula.