Ah I wouldn't count Node as a framework as I'd equate it to the JVM in Java world. But you are right, I'd probably lump webpack in there as it does have a fair bit of depth to it if you want to get the most out of it.
You still need to use Express or something similar on the server side for Javascript, I mean, if we are talking about standard procedures here. Plus with React, you are still doing that Javascript/CSS thingy and HTML of course at some point, so there is no avoiding that, and clearfixes, polyfills, etc, etc.
